People infected with HIV but are stable and taking a combination of potent antiretroviral drugs (known as ART), are still more susceptible to developing TB disease than those who are not HIV-infected because of problems with TB-specific immune responses in their lungs, a new study has revealed
The study, conducted by researchers at the Malawi-Liverpool Wellcome Trust Clinical Research Programme, explains why people taking ART who have undetectable concentration of HIV viruses in their blood and a high T cell count (indicating a good response to ART and a strong immune system) are still susceptible to developing TB disease.